Basically the advice is to wear the prosthesis until it requires cleaning. This is generally once a month. People who take their eye prosthesis out on a daily basis tend to have a lot more problems with comfort.
There is an oily substance in your tears which will coat the prosthesis this takes approximately two days. When the prosthesis is coated, the eye socket no longer recognises the eye as a foreign body and will stop producing moisture to flush it out.
You should have your eye prosthesis professionally polished twice a year. This removes any small scratches and protein build up. It also restores the natural shine which makes the prosthesis more comfortable and aesthetically pleasing.